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Modafinil is a very effective medicine that can help us to stay active and awake. This smart pill is known for its eugeroic nature that will help you if you are suffering from narcolepsy which is an excessive sleep disorder issue and also sleeps apnea and shifts work sleep disorder. This smart pill is the first one that is approved by FDA as a solution to the excessive sleep disorders. Modafinil is also used as a nootropic that can improve the brain functions. It is a medicine with fewer side effects. Though it cannot cure the sleep disorders, it can help a person to stay active and alert throughout the day.
Key ingredient: Modafinil
The excipients of Modafinil are Lactose Monohydrate, Croscarmellose Sodium, Povidone (K-30), and Magnesium Stearate
Modafinil is a smart pill that can help us in staying active and alert. It is the first smart pill that is approved by FDA. To know the history of Modafinil, we have to know about Adrafinil which is also a smart drug that was developed in 1970 by the Lafon Laboratories of France. But, it came out in the research that Adrafinil took a long time as the body had to metabolize it to produce a new substance. After noticing that, the Lafon Laboratories marketed that metabolite substance as a new drug and that is Modafinil. Then in 1986, people had started to use it as a smart pill. In 1998, with the approval of FDA it became the first approved smart pill and now it is used worldwide.
Smart pills are known for boosting up our active energy yet the way of their working is not properly known. According to the experts, the smart pills stimulate the neurotransmitters to boost up our active energy. As a smart pill, Modafinil also follows this working mechanism. The neurons in our brain control the sleep cycle in our body. Dopamine is a type of neurons that keep us active.
To boost up our active energy, Modafinil initially prevents the reuptake of dopamine directly. After that, it indirectly stops the reabsorption of noradrenaline reuptake in the VLPO and orexin activation. For direct stimulation of the receptors, it makes a partial effect on the alpha 1B-adrenergic agonist. To stop the reuptake of dopamine, it binds to the reuptake pump. Thus, it increases the numbers of extracellular dopamine those increase our active energy. It also activates the glutamatergic circuits to inhibit GABA. In this way, the king of smart pills, Modafinil helps us to stay active and alert.
A medicine must be taken with proper dosage if you want to enjoy the effects of the medicine. If you are not taking the medicine with proper dosage, it may not work for you; rather there is the chance that it harms your health. Modafinil is known as the limitless drug that is used for multiple issues. So, according to the issue, dosages are different. The 50 mg dosage of Modafinil is recommended for you if you are using it as a cognitive enhancer. Modafinil dosage of 100 mg should be taken by the patient with narcolepsy. The most used dosage of Modafinil is 200 mg that can treat lots of sleeping disorders. Mostly, it is used by students and entrepreneurs. You can find Modafinil in 400 mg dosage also.
(The information of Modafinil dosage is collected from the internet and so we cannot trust it completely. It is best to take Modafinil with the advice of the doctor to avoid any kind of problem.)
Every medicine has some side effects which are a different person to person. Modafinil also has some side effects but those are less in comparison to other smart pills. Sometimes, when you start taking medicine for the medicine, some conditions arise then which are not so serious. But, go to the doctor if you have any doubt about those conditions which arise after taking Modafinil.
Some of the common side effects of Modafinil are as follows;
Back pain, no appetite, belching, diarrhea etc are some of the not so common side effects of Modafinil. Some also experience dryness of skin and mouth, flushing or redness of the skin, restlessness, heartburn or indigestion, vomiting etc.
Some less common side effects of Modafinil are as follows;
Tegretol), phenytoin (Dilantin), Carbamazepine (Carbatrol, or phenobarbital (Luminal, Solfoton)
rasagiline (Azilect), Isocarboxazid (Marplan), selegiline (Eldepryl, Emsam), phenelzine (Nardil), or tranylcypromine (Parnate)
doxepin (Sinequan), Amitriptyline (Elavil, Etrafon), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), and others
Cyclosporine (Neoral, Sandimmune, Gengraf)
Rifampin (Rifadin, Rimactane, Rifater)
There are other medicines also with which one should avoid taking Modafinil. So, before starting to use Modafinil go to the doctor and inform about the medicines you are already using. Then you can use medicine properly without any problem.
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