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Provigil is a very effective smart pill that helps us to stay active by promoting wakefulness. Basically, it is known for its wakefulness-promoting properties which can help a patient with excessive sleep disorders like narcolepsy, sleep apnea, and shift work sleep disorder. It cannot cure those issues which cause excessive sleep, yet it can help a man in staying awake when he is suffering from any of these. It is also a very effective mood enhancer that can treat fatigue, depression etc. Provigil also can work as an effective nootropic which can improve the cognitive functions like memory, concentration etc.

Provigil is the first brand version of Modafinil which was approved by FDA in 1998. It is a smart pill with the least side effect. As it is the first brand version of Modafinil, we can trust it. Provigil boosts up our active energy by alternating the neurotransmitters in our brain. To enjoy the effect of this medicine, you can buy Provigil from anywhere. You can get it at an affordable price if you buy Provigil online.


Active ingredient: Modafinil

Inactive ingredients: croscarmellose sodium, povidone, lactose monohydrate, microcrystalline cellulose, magnesium stearate, and pregelatinized starch.

History of Provigil

People are using smart drugs for a long period of time. In the ancient period, people used some herbs to increase their stamina so that they can work more for a long period of time. Then with the civilization, new science and technology give us synthetic smart pills. Piracetam is the first smart pill that came to the market in 1960.  Then, in 1970, Lafon Laboratories developed Modafinil which became the first FDA approved smart pill. FDA approved it in the year of 1998 under the brand name of Provigil as the treatment of narcolepsy.

Benefits offered by Provigil

On-label use of Provigil

Narcolepsy: Narcolepsy is a sleep disorder when the patient needs excessive sleep. It happens because of the decrease of orexin in the brain. Provigil helps a patient with narcolepsy by activating the orexin in the brain.

Shift work sleep disorder: This problem of shift work sleep disorder occurs when one is working on the odd hours. Provigil can help a person with this issue to stay awake during the working hours if it is taken before starting work.

Obstructive sleep apnea/hypopnea syndrome (OSAHS): This is a sleeping disorder which affects the breathing during the sleep at night. Because of the shortage of oxygen in our body, in this problem, a person has a very poor quality of sleep which can make him/her sleepy during the work. If you are a patient with OSAHS, take a pill of Provigil in the morning and it can help you to stay awake during the daytime though you have a poor quality sleep at night,

Off-label use

Remove fatigue: Though the research is still going on, Provigil can be an effective solution to the issues related to fatigue.

Reduce ADD/ADHD symptom: As Provigil is the brand version of Modafinil; it can reduce the symptoms of attention deficit disorder or ADD/ADHD. The research is still going on this.

Improve cognitive power: As it has Modafinil as the active ingredient, so the use of Provigil as a nootropic is its most popular off-label use. As a cognitive enhancer, it can improve concentration, learning ability, productivity, focus, memory, and alertness. So, it is famous among the students of higher studies.

The working mechanism of Provigil

Provigil is a very effective smart pill that can help us to stay active and alert. But the working mechanism of Provigil is not clearly known as it is a smart pill. According to the experts, they smart pills work by stimulating the neurotransmitters in the brain, Provigil also follows this mechanism to boost up our activeness as it is also a smart pill.
To boost up our active energy, Provigil lifts up the levels of hypothalamic histamine. To keep us awake, it prevents the movement of dopamine transmitters which control our sleep cycle. By controlling the movement of dopamine, Provigil helps us to stay awake and active. This smart pill is also capable of enhancing our mood. Thus, as a smart pill, Provigil helps us to become a smart and efficient person.

Provigil dosage

To enjoy the effects of a medicine, it is very important to take the medicine with proper dosage. Without taking a medicine with proper dosage, you may not be able to enjoy its effects properly; rather it may harm you. Take Provigil with proper dosage if you want to enjoy the benefits offered by it. If you are using Provigil for narcolepsy, take 200 mg Provigil dosage daily in the morning. The patients with Obstructive sleep apnea/hypopnea are recommended to take Provigil dosage of 200 mg in the starting of the day. The patient with shift work sleep disorder should take Provigil dosage of 200 mg before starting the work shift. It is available in 400 mg dosage also and one can use it also. But don’t take the 400 mg dosage regularly.

(The dosing information of Provigil is collected from the internet for which it may not be 100% corrects. So, it is safe to use Provigil under the observation of the doctor.)

Side effects

You can see side effects in almost all of the medicines which are a different person to person. Provigil also has some side effects. To stay away from the side effects of any medicine, it is best to use the medicine by consulting with the doctor.

After starting to use any allergic reaction like difficulty in breathing, hives, swelling face, lips or tongue, get immediate help from the doctor.

Provigil also can create a serious issue of skin reaction that you may need medical help. Immediately stop using it talk with the doctor if you have to face any of the following;

  • Skin reactions like blisters, peeling or hives.
  • Painful swallowing or sores in the mouth
  • Fever, shortness of breath;
  • Leg swelling
  • Dark urine
  • Jaundice (yellowing of the skin or eyes); or
  • Swelling in the face, tongue, throat or lips

You have to stop taking Provigil and seek medical help immediately if you face any of the conditions discussed below;
If you are suffering from depressing and enjoy or suicidal tendency is developed in your mind Being more active or talkative than usual, unusual thoughts hallucinations, or behavior, aggression Don’t ignore if you are feeling breathing problem, chest pain or irregular heartbeat
Any kind of skin rash either it is minor or major
Some common side effects of Provigil are as follows,

  • A headache
  • Dizziness
  • Anxiety or nervous feeling
  • Back pain
  • Stomach issues like nausea and diarrhea
  • Insomnia (if you overdose)
  • Stuffy nose

Provigil interactions

  • There are some drugs which should not be taken together or interaction can decrease the effect of the drugs and it also can harm you also. There are some drugs and substances which should not be taken with Provigil. So let’s discuss those;
  • Do not take Provigil with some drugs as the interaction can harm us. Some of those drugs are street drugs like methamphetamine, MDMA/”ecstasy”.
  • If you are using hormonal birth control techniques like pills, patch, or ring, before using Provigil tell about it to your doctor and ask him to provide additional reliable birth control methods. Because Provigil can decrease the effectiveness of hormonal birth control and it can cause pregnancy. If you notice any new spotting or breakthrough bleeding, immediately inform the doctor which may be the sign that the birth control is not working.
  • As Provigil has Modafinil as the active ingredient, it may be responsible for immediate removing of the effects of some medicines from our body. Some of those medicines include medicines which are used to treat chronic hepatitis C like asunaprevir, ombitasvir/paritaprevir/ritonavir etc and also axitinib, bosutinib.
  • Some products like cough-and-cold products or diet aids when they are taken them with Provigil, the interaction can increase the heart rate or blood pressure. So, ask your doctor how to use them safely.
  • Provigil or any smart pill when they are taken with caffeine, the effect may become sharper which is not good. So, avoid taking Provigil with any product that contains caffeine.
  • Don’t use other smart pills when you are on Provigil.
  • Alcohol should also be avoided taking with this smart pill. The effect of the interaction of alcohol and Provigil is not known.
  • There are other medicines and substances also which should not be taken with Provigil. To avoid the risk of interaction, take Provigil by consulting with a doctor and inform the doctor about the medicines you are already using.

Use of Provigil

  • Take Provigil orally as a tablet every morning.
  • One can take it with or without food.
  • As it contains Modafinil as the active ingredient, drink more water when you are on Provigil
  • Don’t use it if you are a patient with liver or kidney disease and blood pressure.
  • Provigil should not be used by those whose age is less than 17 years.
  • For the best use of Provigil, take it under the observation of the doctor.

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