The generic waklert is a wonder drug that is used to treat a condition like a narcolepsy, a sleep disorder associated with shift work and obstructive sleep apnea. The main symptoms that are seen in all this disorder are excessive daytime sleepiness or also known as Hypersomnia. It is a condition in which a person feels sleepy all day long. Therefore waklert is designed in such a way that it treats the condition well. The nootropic effect of the medicine is very effective in improving the cognitive senses of the person. So you too can have an enhanced cognitive senses with waklert, and now you can buy waklert onilne.
Waklert usually contains 150 mg of armodafinil as the active ingredient. Apart from these it also contains a few inactive compounds such as magnesium stearate, croscarmellose sodium, lactose monohydrate, microcrystalline cellulose, povidone, and pregelatinized starch.
Waklert is the generic version of the potent drug armodafinil. Improving the memory, alertness and creativity by using Waklert is commo0nly seen. Armodafinil helps to increase the number of monoamines in the people thus causing all the brain functioning’s to improve. These monoamines are a kind of neurotransmitter that is controlled by the hypothalamus of the brain and is responsible for producing hormones that induce wakefulness in a person. This French drug has proven the test of time and over the years has become very popular among the people for treating sleep disorders.
It works by acting in the hypothalamus of the brain. The wakefulness-promoting action of the medicine is similar to the action of the sympathomimetic agent which includes the amphetamine and methylphenidate. This medicine is an indirect dopamine receptor agonist. It is a compound that is a dopamine receptor activator. They activate the signaling pathways through trimetric G-protein thus leading to gene transcription. They bind in-vitro to the dopamine transporter (DAT) and further inhibit the dopamine reuptake.
The activity of the drug has been associated with the in-vivo increase of the extracellular dopamine levels. It is seen that in the genetically modified mice the medicine shows the low effect on the mice that have a lower level of dopamine in them. Thus suggesting that the action of the medicine is largely dependent on the dopamine transporter. But the wake-promoting effect of the medicine is not the antagonist of the dopamine receptor antagonist haloperidol. However, the alpha-methyl-p-tyrosine which is an inhibitor of the dopamine synthesis is responsible for blocking the action of the amphetamine but it does not block the locomotor activity that is induced by the drug. Waklert is keen in producing a psychoactive effect by changing the brain functioning and therefore resulting in the alteration of the behavior, mood and cognitive abilities.
This medicine exhibits a linear time-dependent kinetics that is followed by a single or multiple oral dosage administration. An increase in the systemic exposure is proportional over the dosage range of 50 to 400mg. there were no time-dependent changes seen in the kinetics in 12 weeks of dosing. A steady state of the medicine is seen to reach within 7 days of dosing. And at the steady state, the systemic exposure of the medicine is about 1.8 times the exposure observed after a single dosage.
On taking Armodafinil it gets readily absorb by the body. The insolubility of the medicine is not allowing the determination of the oral bioavailability of the medicine. Achieving the peak plasma concentration takes 2 hours in the non-feeding state. On taking the medicine in feeding state it takes three hours more in determining the bioavailability. Therefore when taking the medicine try to take it after a light meal. As the Tmax is usually associating with the elevating plasma level, therefore, the food can potentially affect the onset of the pharmacologic action of the medicine.
Using Waklert for various medical condition is possible.
When you use other prescribed drugs or even over the counter drug with waklert it might change the effect of the medicine in the body. There is also a chance that it might increase the risk of side effect. Therefore the list of medicine mentioned below reacts with waklert-
The most commonly seen side effect of taking waklert is-
If you ever come across any of the side effect mentioned here then do visit a doctor immediately.
To avoid the occurrence of side effect it is very important to follow the following-
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